Learn more about hydrocodone dosage, including available strengths, forms, and how it's taken. For an opioid-naïve adult, the maximum safe single dose of hydrocodone is 10 mg, with a total daily dose not exceeding 40 mg (8 tablets of 5 mg hydrocodone t. Hydrocodone is a prescription drug used to treat severe pain. Learn about the drug’s dosages, form, strengths, and more. Hydrocodone is available in a variety of formulations for oral administration: [32][33][34] The original oral form of hydrocodone alone, Dicodid, as immediate-release 5- and 10-mg tablets is available for prescription in Continental Europe per national drug control and prescription laws and Title 76 of the Schengen Treaty, but dihydrocodeine has been more widely used for the same indications. Hydrocodone is an orally administered, generic prescription opioid used for chronic pain management. Because of its potential to cause a fatal overdose if misused, following its dosing requirements is vital. Detailed Hydrocodone dosage information for adults. Includes dosages for Chronic Pain; plus renal, liver and dialysis adjustments. 10 mg/325 mg: Maximum 6 tablets daily = 60 mg hydrocodone These limits are often constrained by the 4,000 mg daily acetaminophen ceiling required to prevent hepatotoxicity, which frequently becomes the limiting factor before reaching maximum hydrocodone doses. 1, 2 Extended-Release Single-Entity Hydrocodone The standard generic Vicodin dosage for moderate to severe pain is 2.5 mg/325 mg to 10 mg/325 mg every 4-6 hours as needed. Use our hydrocodone/acetaminophen dosage chart to find the recommended and maximum doses of hydrocodone/acetaminophen. Hydrocodone is a potent opioid used to manage severe and persistent pain that requires an extended treatment period with a daily opioid pain medicine, when other non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Hydrocodone can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong opioid pain medicines. Make sure you store the medicine in a safe and secure place to prevent others from getting it.